Relief is 2 hours faster with ZYRTEC® vs Claritin®†1
In 2 EEU studies‡: ZYRTEC® worked 3 times faster than Claritin® (1 hour vs 3 hours)†1,2
33% greater relief at 21 to 24 hours with ZYRTEC® vs Allegra®§3
In another EEU study‡: ZYRTEC® delivered greater relief than Allegra® at 21 to 24 hours (postdose)§3
ZYRTEC® provides allergy relief that satisfies patients' needs
93% of patients reported satisfaction with prescription ZYRTEC®
in a survey of more than 180,000 respondents||4
*Among name brand OTC products
†ZYRTEC® 10 mg starts working at hour 1 and Claritin® starts working at hour 3 based on the first dose on the first day of a 2-day study in 2 pollen chamber studies. Primary end point measured mean improvement from baseline in major symptom complex (MSC) severity score. MSC severity score included runny nose, sniffles, itchy nose, nose blows, sneezes, and watery eyes.
‡The environment exposure unit (EEU) is an indoor chamber used to expose large groups of subjects to controlled levels of pollen comparable to those experienced outdoors during peak allergy season and can be replicated regardless of time of year. The EEU is a validated, standard method of determining onset of action and duration of anti-allergic treatments.
§Based on a 2-day pollen chamber study with ZYRTEC® 10 mg. Significant relief vs Allegra at hours 21 to 24. Primary end point measured mean improvement from baseline in total symptom severity complex (TSSC) score at hours 21 to 24. TSSC score included runny nose, sneezing, itchy nose/palate/throat, and itchy/watery eyes.
||Based on a consumer satisfaction telephone survey of 180,643 patients who took prescription ZYRTEC® between 1999 and 2002.
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References:
1Day JH, Briscoe M, Widlitz MD. Cetirizine, loratadine, or placebo in subjects with seasonal allergic rhinitis: effects after controlled ragweed pollen challenge in an environmental exposure unit. J Allergy Clin Immunol. 1998;101:638-645.
2Day JH, Briscoe M, Rafeiro E, Chapman D, Kramer B. Comparative onset of action and symptom relief with cetirizine, loratadine, or placebo in an environmental exposure unit in subject with seasonal allergic rhinitis: confirmation of a test system. Ann Allergy Asthma Immunol. 2001;87:474-481.
3Day JH, Briscoe M, Rafeiro E, Hewlett D Jr, Chapman D, Kramer B. Randomized double-blind comparison of cetirizine and fexofenadine after pollen challenge in the Environmental Exposure Unit: duration of effect in subjects with seasonal allergic rhinitis. Allergy Asthma Proc. 2004;25:59-68.
4Data on file, McNEIL-PPC, Inc.