TOTAL ALLERGY CARE for HEALTH PROFESSIONALS
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ZYRTEC® Clinical Data

ZYRTEC® provides consistent relief from seasonal allergic rhinitis (SAR) over a 2- to 4-week treatment period*1

Line graph of seasonal allergic rhinitis relief over 4 weeks Line graph of seasonal allergic rhinitis relief over 4 weeks

References

Ocular Symptoms

Proven consistent relief of bothersome itchy, watery eyes in SAR patients through Week 12

Line graph of seasonal allergic rhinitis ocular symptom relief over 7 days Line graph of seasonal allergic rhinitis ocular symptom relief over 7 days

  • Improvement in Total Ocular Symptom Score (TOSS) during the first week of treatment
  • Large, multicenter study of 1255 seasonal allergy patients; most with moderate/severe symptoms based on a 4-point scale (0=none to 3=severe)
References

Relief of ocular symptoms continued over the 2-week treatment period†2

Line graph of seasonal allergic rhinitis ocular symptom relief over 2 weeks Line graph of seasonal allergic rhinitis ocular symptom relief over 2 weeks

  • 35% to 62% mean improvement from baseline in ocular scores
References

Nasal Symptoms

Powerful relief of sneezing, runny nose, and itchy nose in SAR patients3

Line graph of seasonal allergic rhinitis nasal symptom relief over 7 days Line graph of seasonal allergic rhinitis nasal symptom relief over 7 days

  • Improvement in Total Nasal Symptom Score (TNSS) in the first week of treatment
  • Large, multicenter study included 921 patients with SAR; most with moderate/severe symptoms based on a 4-point scale (0=none to 3=severe)
References

Significant improvement continued over the 2-week treatment period3

  • 29% to 63% mean improvement from baseline in nasal severity scores

*All studies are multicenter, randomized, placebo-controlled, double-blind, minimum 100 participants with previous diagnosis of SAR, and adequate minimum duration (2 weeks). Total symptom severity score measured by patient.

Randomized, placebo-controlled studies of SAR patients (N=1255). Total ocular symptom score (TOSS) was the sum of the severity scores for itchy eyes and watery eyes; one study also included red eyes. Individual symptom scores were rated on a 4-point scale (0=none to 3=severe). SAR 1 was 1 week in duration.

Randomized, placebo-controlled studies of SAR patients (N=921). Total Nasal Symptom Score (TNSS) was the sum of the severity scores for sneezing, runny nose, itchy nose in all studies; 2 studies included post-nasal discharge. Individual symptom scores were rated on a 4-point scale (0=none to 3=severe). SAR 1 was 1 week in duration.

References: 1. Data on file, Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division. 2. Patel M, Urdaneta E, Franklin K, et al. Cetirizine significantly relieves ocular allergy symptoms in subjects with seasonal allergic rhinitis. Poster Abstract. Data on file, Johnson & Johnson Consumer Inc., McNeil Consumer Health Division. 3. Urdaneta E, Tian X, Wu M, et al. Cetirizine effectively relieves both ocular allergy symptoms and nasal allergy symptoms in subjects with seasonal allergic rhinitis. Poster Abstract. Data on file, Johnson & Johnson Consumer Inc., McNeil Consumer Health Division.

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