Efficacy in Perennial Allergies

ZYRTEC® provides consistent relief for patients with perennial allergic rhinitis

See the data, and recommend ZYRTEC® for your patients who suffer from indoor allergies.

ZYRTEC® starts working at hour 12,3†

For your patients with allergies, choose ZYRTEC®.

33% greater relief vs Allegra® at 21 to 24 hours4‡

Make ZYRTEC® your foundation for allergy relief.

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*All studies are multicenter, randomized, placebo-controlled, double-blind, minimum 100 participants with previous diagnosis of PAR, and adequate minimum duration (4 weeks). Total symptom severity measured by patient.

†ZYRTEC® 10 mg starts working at hour 1, based on first dose on the first day of a 2-day study in 2 pollen-chamber studies. Primary endpoint measured mean improvement from baseline in Major Symptom Complex (MSC) severity score. MSC symptoms included runny nose, sniffles, itchy nose, nose blows, sneezes, and watery eyes.

‡Based on first dose on the first day of a 2-day pollen-chamber study with ZYRTEC® 10 mg vs Allegra® 180 mg at hours 21 to 24. Primary efficacy endpoint was change in total symptom severity score from baseline at hours 21 to 24. Total symptom severity complex score was defined as the sum of self-assessed severity scores of 4 symptoms: runny nose, sneezing, itchy nose/palate/throat, and itchy/watery eyes.

References: 1. Data on file. Johnson & Johnson Consumer Inc., McNeil Consumer Health Division. 2. Day JH, Briscoe M, Widlitz MD. Cetirizine, loratadine, or placebo in subjects with seasonal allergic rhinitis: effects after controlled ragweed pollen challenge in an environmental exposure unit. J Allergy Clin Immunol. 1998;101(5):638-645. 3. Day JH, Briscoe M, Rafeiro E, Chapman D, Kramer B. Comparative onset of action and symptom relief with cetirizine, loratadine, or placebo in an environmental exposure unit in subjects with seasonal allergic rhinitis: confirmation of a test system. Ann Allergy Asthma Immunol. 2001;87(6):474-481. 4. Day JH, Briscoe MP, Rafiero E, Hewlett D, Chapman D, Kramer B. Randomized double-blind comparison of cetirizine and fexofenadine after pollen challenge in the environmental exposure unit: duration of effect in subjects with seasonal allergic rhinitis. Allergy Asthma Proc. 2004;25(1):59-68.